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CD41a

"gpIIb, CD41a"

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Antigen Preparation

Recombinant protein of human CD41a

Background

"CD41 is a 125/25 kD subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIb?) and light chain (gpIIb?) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, and thrombin."

PURIFICATION The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping	SPECIFICITY This antibody recognizes human CD41a. The other species are not tested.
FORMULATION 0.01M Phosphate-Buffered Saline (pH7.2-7.4) with 0.01% NaN3 + antibody stabilizer	STORAGE The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

3674

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

5-10 µg/10^6 cells

Order Info

Catalog #:	606-600
Lot #:
Size:	100ug/200ul
Host:	Mouse
Clone:	HIP8
Isotyping:	IgG1
Applications:	"IHC(P), FC"
Reactivity:	Hu
Price:	$ 245.00

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