SLC10a4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
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Antigen Preparation
A fragment of oligo-peptide derived from extracellular domain of mouse/rat N-terminal SLC10A4 protein.
Background
"The SLC10 family, or the solute carrier family, formally named the “sodium/bile salt cotransporter familyâ€, contains over 50 members in animal, plant and bacterial species. In human, two well-characterized members and three orphan transporters are known. The Na+/taurocholate cotransporting polypeptide (NTCP; SLC10A1) and the apical sodium-dependent bile salt transporter (ASBT; SLC10A2) are critical components of the enterohepatic circulation of bile salts. SLC10A4/Slc10a4 has a phylogenetic relationship to the SLC10A1 and SLC10A2. The rat SLC10A4 protein consists of 437 aa and exhibits a seven transmembrane domain topology with Nexo/Ccyt trans-orientation of the N- and C-terminal ends. The SLC10A4 protein is highly expressed in brain and placenta. "
PURIFICATION
The Rabbit IgG is purified by Epitope Affinity Purification
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SPECIFICITY
This antibody recognizes ~48 kDa of SLC10A protein. It is cross react to mouse and rat. The other species are not tested.
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FORMULATION
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
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STORAGE
The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
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Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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