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RIC8

Resistance to inhibitors of cholinesterase 8 homolog; RIC-8; RIC8A

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Antigen Preparation

Resistance RIC8

Background

"RIC8, guanine nucleotide exchange factor A, a 520-amino acid protein, belongs to member of the Synembryn family. The cellular localization is predicted to be cytoplasmic. RIC-8 was originally found by genetic studies on C. elegans mutants that were resistant to inhibitors of acetylcholinesterase and reported to act in vitro as a guanine nucleotide exchange factor for G protein alpha subunits. Ric-8A was translocated to the cell membrane in response to the G-coupled receptor stimulation. It enhances ERK activation and the guanine nucleotide exchange activity. "

PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification	SPECIFICITY This antibody recognizes human RIC8 protein. The other species are not tested.
FORMULATION This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer	STORAGE The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

Not tested

Order Info

Catalog #:	620-570
Lot #:	See the label
Size:	100ug/200ul
Host:	Rabbit
Clone:
Isotyping:	Rabbit IgG
Applications:	IHC(P), WB
Reactivity:	Hu, Ms, Rt
Price:	$ 245.00

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