Antigen Preparation
"A synthetic peptide corresponding to the C-terminus of human FOXP4 protein. This sequence is identical within human, mouse, rat origins."
Background
"Forkhead/winged-helix box (Fox) genes are the transcriptional regulators and highly conserved across mammals. It contains a FOX DNA-binding domain and large polyglutamine tract. The FOXPs are involved in organogenesis and cell differentiation. Foxp1, Foxp2 and Foxp4 are the core of a multi-protein complex that regulates diverse aspects of tissue-restricted gene expression during development in a way distinct from other FOX proteins. The FOX 1/2/4 activity is regulated by homo- and heterodimerization. "
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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