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SMN (Survival of motor neuron)
survival of motor neuron 1; SMN

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Antigen Preparation
A synthetic peptide corresponding to C-terminus of human SMN.
Background
"The survival motor neuron (SMN) protein is the protein product of the spinal muscular atrophy (SMA) disease. SMN gene is the SMA determining gene. In humans, there are two nearly identical copies of the survival of motor neuron genes (SMN1 and SMN2), whereas other eukaryotic species have only one copy of the SMN gene. SMN is expressed ubiquitously and is a core component of a self-assembling multiprotein complex. The SMN complex, consisting of SMN and Gemin proteins (Gemin2, -3, -4, -5, -6, -7 and –8), in which SMN-Gemin2 complex plays an essential role in the assembly and regeneration of small nuclear ribonucleoproteins (snRNPs) and spliceosomes."
PURIFICATION
The Rabbit IgG is purified by Epitope Affinity Purification
SPECIFICITY
This antibody recognizes ~35 kDa of human SMN protein. The other species are not tested
FORMULATION
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
STORAGE
The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Gene ID
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5 µg/ml
IHC
2-10 µg/ml
Flow cytometry
Not tested
Order Info
Catalog #: 601-720
Lot #: See the label
Size: 100ug/200ul
Host: Rabbit
Clone:
Isotyping: Rabbit IgG
Applications: IHC(P), WB
Reactivity: Hu
Price: $ 245.00
REFERENCES
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