dNK (Deoxynucleoside Kinase)
DNK, 2'-deoxynucleoside kinase, DM-dNK
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Antigen Preparation
A synthetic peptide corresponding to the N-terminus of fruit fly Deoxynucleoside kinase protein.
Background
"Deoxynucleoside kinases (dNK) are key enzymes in deoxyribonucleoside salvage, activating several clinically important chemotherapeutic drugs. Deoxynulceoside kinases catalyze the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribocytidine kinase (dCK), deoxyriboguanosine kinase(dGK), cytosolic thymidine kinase(TK1) and mitochondrial thymidine kinase (TK2). "
PURIFICATION
The Rabbit IgG is purified by Epitope Affinity Purification
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SPECIFICITY
This antibody recognizes ~~30 kDa of dNK protein. The other species are not tested.
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FORMULATION
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
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STORAGE
The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
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Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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