Antigen Preparation
A synthetic peptide DS DAE NEQ NHD PNV EEF LQQ QDT corresponding to human ZEB1 protein
Background
"ZEB1 is a zinc finger transcription factor. It plays a role in transcriptional repression of interleukin 2. ZEB1 is primarily expressed in the mesoderm, but changes in the level of expression during tissue maturation suggest a role for ZEB1 in the early histogenesis of mesodermal tissues. In addition to its role as an embryonic gene regulator, ZEB1 is also involved in regulating the development of certain skeletal structures. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy."
Applications/Suggested Working Dilutions
|
|
|
Immunoprecipitation
2-5 µg/ml
|
|
Flow cytometry
Not tested
|