Antigen Preparation
A synthetic peptide corresponding to EQKAHLEDYYW MTGYPRQ. This sequence is identical to human, mouse, rat.
Background
"MAF is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. MAF increases T cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, it transactivates strongly the glucagon gene promoter through the G1 element. MAF activates transcription of the CD13 proximal promoter in endothelial cells. It is involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. "
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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