Antigen Preparation
A synthetic peptide of human Cyclin A2
Background
"Cyclin A2 belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M. Cyclin A2 is expressed in dividing somatic cells. Increased expression of cyclin A2 has been observed in many types of cancer. Cyclin A2 was predicted as a potential differential marker of splenic diffuse red pulp small B-cell lymphoma. Studies indicate that cyclin A2 is a biomarker for the prognosis of ER+ breast cancer."
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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