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CD16

CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; FcGRIIIA

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Antigen Preparation

A recombinant protein of human CD16

Background

"CD16 is known as a receptor for the immunoglobulin G Fc gamma receptor IIIa (FCGR3A). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcÎ³RIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcÎ³RIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. CD16 is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. "

PURIFICATION The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping	SPECIFICITY This antibody recognizes human CD16 protein. The other species are not tested.
FORMULATION This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer	STORAGE The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

2214

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

0.5-5 µg/106 cells

Order Info

Catalog #:	605-230
Lot #:
Size:	100ug/200ul
Host:	Mouse
Clone:	3G8
Isotyping:	IgG1
Applications:	IHC(P), FC
Reactivity:	Hu
Price:	$ 245.00

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