Connexin 32
Gap junction beta-1 protein, Connexin-32, Cx32, GAP junction 28 kDa liver protein
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Antigen Preparation
"A synthetic peptide of C-terminus of Connexin 32. This sequence is identical to human, mice and rat. "
Background
"Connexin-32 is a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Connexin 32 (Cx32) is a fundamental protein in the peripheral nervous system (PNS)."
PURIFICATION
The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
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SPECIFICITY
"This antibody recognizes human Connexin 32 protein. It cross reacts to human, mice and rat. "
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FORMULATION
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
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STORAGE
The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
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Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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