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Thyroglobulin

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Antigen Preparation

A recombinant protein of human Thyroglobulin

Background

Thyroglobulin (Tg) is a dimeric glycoprotein that is predominantly produced by follicular cells of the thyroid. This protein is secreted from the endoplasmic reticulum to the follicular lumen. Tg acts as a substrate for the synthesis of thyroxine (T4) and triiodothyronine (T3) as well as storage of inactive forms of thyroid hormone and iodine.

PURIFICATION The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping	SPECIFICITY This antibody recognizes human Thyroglobulin protein. The other species are not tested.
FORMULATION This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer	STORAGE The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

Not tested

Order Info

Catalog #:	604-740
Lot #:
Size:	100ug/200ul
Host:	Mouse
Clone:	ZY460
Isotyping:	IgG1
Applications:	IHC(P)
Reactivity:	Hu
Price:	$ 245.00

REFERENCES

"Sellitti DF, Suzuki K. 2014. Thyroid 24(4):625"