Troponin T
CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT
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Antigen Preparation
Highly purified human cardiac troponin T
Background
"Cardiac Troponin T, a 35.4kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the
thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion
concentration. Mutations within the protein have been associated with familial hyper-trophic cardiomyopathy as well as with
dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.
"
PURIFICATION
The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
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SPECIFICITY
This antbody recognizes human Troponin T . The other species not tested.
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FORMULATION
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
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STORAGE
The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
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Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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