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CD31(PECAM)

CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM

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Antigen Preparation

Membrane preparation of a spleen from a patient with hairy cell leukemia.

Background

"CD31 is a cell surface glycoprotein expressed on endothelial cells and in platelets. It is known to be involved in cell signaling and cell adhesion. The proteinmay be a component involved in the interaction of endothelial cells with coagulation factors, platelets, and the subendothelial matrix. It is found on the surface of platelets, monocytes, neutrophils, and some types of T- cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. "

PURIFICATION The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping	SPECIFICITY This antibody recognizes human Cd31.The other species was not tested.
FORMULATION This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer	STORAGE The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

Not tested

Order Info

Catalog #:	500-1274
Lot #:
Size:	100ug/200ul
Host:	Mouse
Clone:	JC70
Isotyping:	IgG1
Applications:	IHC(P), WB
Reactivity:	Hu
Price:	$ 245.00

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