Antigen Preparation
A recombinant protein of human EpCAM
Background
"EpCam, the epithelial cell adhesion molecule, is a carcinoma-associated antigen and a member of a family that includes at least two type I membrane proteins. EpCAM is a monomeric membrane glycoprotein that is expressed in most normal human epithelium and carcinomas. It is overexpressed in a variety of carcinomas and is, therefore, a potential target for the visualization and therapy of human solid tumors. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy."
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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