Antigen Preparation
A recombinant protein ITGB1
Background
"Integrin beta-1 (ITGB1) is a cell surface receptor. Integrins are heterodimeric proteins made up of alpha and beta subunits. Both alpha and beta integrin subunits have large extracellular, single membrane-spanning, and small cytoplasmic domains. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. Integrin beta-1 is the most abundant beta-integrin expressed and associates with at least 10 different integrin-alpha subunits."
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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