Abbomax

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EGFR 1

epidermal growth factor receptor; HER1; Proto-oncogene c-ErbB-1

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Antigen Preparation

An Extracellular domain of human recombinant EGFR protein as an immunogen

Background

"EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas."

PURIFICATION The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping	SPECIFICITY "This antbody recognizes EGFR 1 protein. It cross reacts with human, mice and rat . The other species not tested."
FORMULATION This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer	STORAGE The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

1956

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

Not tested

Order Info

Catalog #:	500-6694
Lot #:	See the label
Size:	100ug/200ul
Host:	Mouse
Clone:	ABM341
Isotyping:	IgG1
Applications:	IHC(P), WB
Reactivity:	Hu, ms, Rt, Bovine, Chicken, Guinea Pig
Price:	$ 245.00

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