Insulin Receptor (IR)
Insulin receptor; CD220; IR
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Antigen Preparation
Highly purified human placental Insulin Receptor.
Background
"The human insulin receptor is a heterotetrametric membrane glycoprotein consisting of disulfide-linked subunits in a β-α-α-β Configuration. The beta-subunit (95kDa) possesses a single transmembrane domain, whereas the alpha subunit (135kDa) is completely extracellular."
PURIFICATION
The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
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SPECIFICITY
This antibody recognizes human Insulin Receptor protein. The other species was not tested.
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FORMULATION
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
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STORAGE
The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
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Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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