Abbomax

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IFN gamma

Interferon, gamma; IFNG

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Antigen Preparation

A synthetic peptide corrsponding to the internal segment of human IFN gamma

Background

"Interferon (IFN)-Î³ is an antiviral and antiparasitic agent produced by CD4+/CD8+ lymphocytes and natural killer cells that undergo activation by antigens, mitogens or alloantigens. IFN-Î³ production modulates T cell growth and differentiation and inhibits the growth of B cells. Synthesis of IFN-Î³ is inducible by IL-2, FGF and EGF. The active form of IFN-Î³ is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-Î³ is stabilized by non-covalent interactions through the interface of the helices. IFN-Î³ translated precursor is 166 amino acids, including the 23 amino acid secretory sequence. Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers."

PURIFICATION The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping	SPECIFICITY This antbody recognizes human IFN gamma. The other species not tested.
FORMULATION This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer	STORAGE The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

Not tested

Order Info

Catalog #:	500-4584
Lot #:	See the label
Size:	100ug/200ul
Host:	Mouse
Clone:	ABM153
Isotyping:	IgG1
Applications:	IHC(P), ELISA
Reactivity:	Hu
Price:	$ 245.00

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