Antigen Preparation
"A synthetic peptide corresponding to C-terminus of OCT-2 protein from human, mouse and rat origins."
Background
"Oct1 and Oct2 are transcription factors of the POU homeo-domain family that bind to the Ig gene octamer sites, regulating B-cell-specific genes. The function of these transcription factors is dependent on the activity of B-cell-restricted coactivators such as BOB.1/OBF.1.Absence of functional Oct-2 and Bob-1 cells represents a novel mechanism for immunoglobulin gene deregulation"
Applications/Suggested Working Dilutions
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Immunoprecipitation
2-5 µg/ml
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Flow cytometry
Not tested
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