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PDGF
platelet-derived growth factor, alpha polypeptide; PDGFA

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Antigen Preparation
"A fusion recombinant protein derived from E Coli, containing 196aa- full length of human PDGF protein"
Background
"The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of homo/hetero dimeric proteins, PDGF-AA, -BB, -CC, -DD and -AB. The PDGF-AA, -BB and AB bind to alpha type receptor, while beta type receptors bind to PDGF-BB and PDGF-AB. Upon activation by PDGF, the receptors get dimerised and auphosphorylated in several sites on its receptors (Receptor tyrosine kinase) in cytosolic domain to trigger cell signaling through PI3K pathway. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms."
PURIFICATION
The Rabbit IgG is purified by Epitope Affinity Purification
SPECIFICITY
This antibody recognizes ~23 kDa of human PDGF protein. The other species are not tested.
FORMULATION
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
STORAGE
The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Gene ID
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5 µg/ml
IHC
2-10 µg/ml
Flow cytometry
Not tested
Order Info
Catalog #: 500-3894
Lot #: See the label
Size: 100ug/200ul
Host: Rabbit
Clone:
Isotyping: Rabbit IgG
Applications: IHC(P), WB, IF
Reactivity: Hu, Rt, Ms
Price: $ 245.00
REFERENCES
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