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GABA Receptor 1

GABA receptor 1

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Antigen Preparation

A synthetic peptide derived from N-term of human GABA receptor 1 protein. This sequence is identical to human and rat.

Background

"Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. It acts at GABA receptors to produce fast synaptic inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The overexpression of one particular gene encoding for G-protein-activated inward rectifying potassium type 2 (GIRK2) channel subunit and its coupling to GABA(B) receptors may contribute to a range of mental and functional disabilities "

PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification	SPECIFICITY This antibody recognizes ~100 kDa of GABA Receptor 1 Protein. It is cross react to human and rat. The other species are not tested.
FORMULATION This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer	STORAGE The antibodies are stable for 24 months from date of receipt when stored at –20oC to –70oC. The antibodies can be stored at 2oC-8oC for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

Not tested

Order Info

Catalog #:	500-2884
Lot #:	See the label
Size:	100ug/200ul
Host:	Rabbit
Clone:
Isotyping:	Rabbit IgG
Applications:	IHC(P), WB, IP
Reactivity:	Hu, Ms, Rt
Price:	$ 245.00

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