Abbomax

Career

L1CAM(pS1152)

L1 cell adhesion molecule; CD171

Antigen Preparation

N/A

Background

The cell adhesion molecule L1 (L1CAM) is an axonal glycoprotein which belongs to the immunoglobulin supergene family. The ectodomain,consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic raplegia and hydrocephalus). The malfunction of LaCAM may contribute to neurological and cancerous diseases.

PURIFICATION The Rabbit IgG is purified by site-modified Epitope Affinity Purification.	SPECIFICITY N/A
FORMULATION This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.	STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

Gene ID

16728

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5 µg/ml

IHC

2-10 µg/ml

Flow cytometry

5-10 µg/ml

Order Info

Catalog #:	601-070
Lot #:	See the label
Size:	100ug
Host:	Rabbit
Clone:
Isotyping:
Applications:	ELISA, WB
Reactivity:	Hu/Rt/Ms
Price:	$ 325.00

REFERENCES

Lane DP and EB Lane. A rapid antibody assay system for screening hybridoma cultures, J. Immunol. Methods, 47: 303-307 (1981)