cyclic adenosine monophosphate (cAMP)

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Product Preparation
A chemically linked 3’, 5’-Cyclic Adenosine Monophosphate (cAMP)
Background
Cyclic adenosine monophosphate (cAMP) is an intracellular mediator that plays an important role in a variety of hormone signaling. It’s been known as an universal cytoplasmic second messenger in drug discovery due to the involvement of G-Protein Coupled Receptors (GPCR) signaling events where the receptors are activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, etc.
PURIFICATION
The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
SPECIFICITY
This antibody recognizes cAMP, not cross react with 5/-AMP, 5’-ADP, 5’-ATP or 3’, 5’-cGMP.
FORMULATION
This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
STORAGE
The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Gene ID
N/A
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5 µg/ml
IHC
2-10 µg/ml
Flow cytometry
5-10 µg/ml
Order Info
Catalog #: 500-9534
Lot #: See the label
Size: 100 ug
Host: Mouse
Isotyping: Mouse IgG1
Applications: WB
Reactivity: Hu, Ms, Rt
Price: $ 319.00
REFERENCES
Chika Funaki, et al, Role of cAMP inhibition of p44/p42 mitogen-activated protein kinase in potentiation of protein secretion in rat lacrimal gland. Am J Physiol Cell Physiol 293: C1551-C1560, 2007.
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