Katanin, P80
Katanin P80

Product Preparation
A Human B cell nuclei from plasmacytoid 2p68 cells
Background
The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase that phosphorylates certain ranscription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. This antibody recognizes p70/p80 dimer which is destroyed during Western Blot.
PURIFICATION
The antibody is purified from Ascites fluid by Protein G
SPECIFICITY
FORMULATION
This affinity purified antibody is supplied in sterile Phosphate-buffered saline (pH7.2) containing antibody stabilizer.
STORAGE
The antibodies are stable for 12 months from date of receipt when stored at –20oC to –70oC
Gene ID
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
N/A
Immunoprecipitation
1-5 µg/ml
IHC
1:50
Flow cytometry
N/A
Order Info
Catalog #: 500-6004
Lot #: See the label
Size: 100 ug
Host: Mouse
Isotyping: IgG2a
Applications: IHC(P); IP; IF
Reactivity: Human
Price: $ 299.00
REFERENCES
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